![]() The Proton Therapy Center in Cincinnati is a state-of-the-art facility that features cutting-edge technology and equipment, allowing researchers to develop and test new treatments for a wide range of malignancies. "Our dedicated team of researchers, clinicians, and staff are committed to advancing the field of cancer treatment and finding new ways to improve patient outcomes," said John Breneman, MD, medical director of the Cincinnati Children's/UC Medical Center Proton Therapy Center, who is principal site investigator for the FAST-02 clinical trial. However, until recently, the technology to deliver FLASH radiation for cancer patients was not available. In pre-clinical testing, FLASH proton therapy has been shown to potentially reduce side effects of radiation treatment compared to conventional radiation. Ten adults whose metastatic cancer has spread to their chest bones will participate in the research clinical trial of FLASH proton therapy. Now, Cincinnati Children's researchers are collaborating with University of Cincinnati researchers to establish the efficacy of ultra-high dose rate proton therapy in treating painful bone metastases in the chest. The FAST-02 study is sponsored by Varian, a Siemens Healthineers company. That study focused on people with bone metastases in the extremities. The new study, called FAST-02, marks a significant achievement for the Proton Therapy Center in Cincinnati, which continues to lead the way in global research in the field of FLASH proton therapy.įAST-02 follows a breakthrough last year in the world's first clinical trial of FLASH proton therapy in people, the FAST-01 study ( Fe Asibility Study of FLASH Radiotherapy for the Treatment of Symptomatic Bone Metastases). Research in the laboratory suggests that FLASH may result in fewer side effects than standard forms of radiation delivery, and the clinical trial is testing the feasibility of FLASH to treat people with cancer. ![]() "This trial of ultra-high dose rate proton therapy is just one of our efforts to develop innovative cancer treatments."įLASH is an investigational mode of radiation therapy delivery that can be administered to a patient in less than 1 second.
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